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Test Code HEPCAB Hepatitis C Antibody (HCV Ab)

Important Note

As of 9/1/2023, all Hepatitis C Virus (HCV) antibody screens that are positive will automatically reflex the HCV RNA by transcription polymerase chain reaction at an additional charge.  Per the CDC testing recommendations, anti-HCV positive/reactive should be automatically tested with an FDA-approved nucleic acid test (NAT) for detection of HCV RNA.  "Automatic" testing happens in the laboratory without additional action on the part of the patient or the healthcare provider.  Automatic testing is critical to increase the number of people diagnosed with current HCV infection who can then be linked to care and curative antiviral therapy.

Please note the following interpretations for this test:

Non-Reactive: Samples with S/CO <0.80 are considered non-reactive for HCV antibodies.

Equivocal: >0.80 and <1.00 S/CO - retest in duplicate to confirm initial result. Samples having at least 2 out of 3 results equal or above S/CO value of 1.0 are considered reactive. Samples having at least 2 out of 3 results less than S/CO value of 1.0 are considered non-reactive.

Reactive: Samples with S/CO values >1.00 are considered reactive for HCV antibodies.

Infectious

Additional Codes

MEDITECH MNEMONIC:

HEPCAB

Specimen Requirements

Preferred Specimen:

2.5mL serum from a gel tube (includes reflex to HCV RNA Quantitative test referred to Mayo Clinical Laboratories, if needed)

 

Acceptable Specimen:

2.5mL serum from a non-gel tube (includes reflex to HCV RNA Quantitative test referred to Mayo Clinical Laboratories, if needed)

 

Minimum Volume:

0.5mL serum from a gel or non-gel tube (volume does not include repeat or reflexed testing)

Transport Temperature/Stability

Transport Container:

Transport Tube

 

Preferred Transport Temperature:

Ambient

 

Specimen Stability (after centrifugation):

Ambient:  <4 days

Refrigerated:  <7 days

Frozen:  <3 months

 

Setup Schedule:

SUN-SAT

Performing Laboratory

Willis Knighton Medical Center

2600 Greenwood Road

Shreveport, LA  71103