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Test Code FLUOX Fluoxetine, Serum

Important Note

**Specimens collected in gel tubes are not acceptable**

**This test name is similar to FLUOXAMINE.  Please confirm the name of the test prior to ordering**

Additional Codes

Aliases: 

Fluoxetine (Prozac)

Norfluoxetine

Prozac (Fluoxetine Hydrochloride)

Reporting Name

Fluoxetine, S

Useful For

Monitoring serum concentration of fluoxetine during therapy

 

Evaluating potential toxicity

 

Evaluating patient compliance

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Serum

Collection Instructions:

1. Draw blood immediately before the next scheduled dose (trough).

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reference Values

Fluoxetine + Norfluoxetine: 120-500 ng/mL

Day(s) Performed

Wednesday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLUOX Fluoxetine, S 78437-1

 

Result ID Test Result Name Result LOINC Value
80228 Fluoxetine, S 74982-0
251 Norfluoxetine, S 3868-7
252 Fluoxetine+Norfluoxetine 74948-1

Report Available

1 to 8 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.