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Test Code C1ES C1 Esterase Inhibitor Antigen, Serum

Important Note

IF ORDERING THIS TEST WITH OTHER COMPLEMENT TESTS, DO NOT COLLECT GEL/SST SPECIMENS!

 

Per Mayo, the most important thing about processing Complement Testing is keep the specimen COLD (< 10⁰C)!  Ice packs can be used to collect, and the blood should clot on ice or refrigerated. Ice packs warm up quickly so you must monitor and change the ice packs when they warm up if using ice packs to clot. Once the blood has clotted, it should be spun down and FROZEN IMMEDIATELY. 

Reporting Name

C1 Esterase Inhibitor Antigen, S

Useful For

Diagnosis of hereditary angioedema

 

Monitoring levels of C1 esterase inhibitor in response to therapy

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparations: Fasting preferred but not required.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. Centrifuge and aliquot serum into plastic vial.

3. Freeze specimen within 30 minutes.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 28 days
  Refrigerated  28 days
  Ambient  72 hours

Reference Values

19-37 mg/dL

Day(s) Performed

Monday through Friday

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83883

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C1ES C1 Esterase Inhibitor Antigen, S 4477-6

 

Result ID Test Result Name Result LOINC Value
C1ES C1 Esterase Inhibitor Antigen, S 4477-6

Report Available

2 to 5 days

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Method Name

Nephelometry